Conte Center for Neuroimmune Studies |

Studying brain illness through neuroscience, immunology, and genomics.

We apply diverse scientific disciplines and technologies to investigate the fundamentals of brain-related disorders (such as schizophrenia and Alzheimer’s disease), and how we can treat or reverse their effects.

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Complement RNA across the Adult Mouse Brain
Spatial distribution of RNA molecules for C1qa (green), Nptx1 (light blue), Nptx2 (orange), C4b (red) and Cd55 (dark blue) labeled by MERFISH.

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Genetic Risk Factor for Schizophrenia
In health, Complement C4 (green) is restricted to blood vessels, but during neurodegeneration, astrocytes (red) become reactive and secrete C4 into the brain tissue.

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Nontraditional Circuitry
Cortically-projection neurons (red) send their axons into the insular cortex of the mouse globus pallidus externus (GPe, green).

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Visualizing Neurons in Culture
Homer1 (orange) and Bassoon (red) localize to the synapses of healthy neurons (blue), while Protein Kinase A (green) is found all over.

Complement RNA across the Adult Mouse Brain
Spatial distribution of RNA molecules for C1qa (green), Nptx1 (light blue), Nptx2 (orange), C4b (red) and Cd55 (dark blue) labeled by MERFISH.
READ MORE >

Genetic Risk Factor for Schizophrenia
In health, Complement C4 (green) is restricted to blood vessels, but during neurodegeneration, astrocytes (red) become reactive and secrete C4 into the brain tissue.
READ MORE >

Nontraditional Circuitry
Cortically-projection neurons (red) send their axons into the insular cortex of the mouse globus pallidus externus (GPe, green).
READ MORE >

Visualizing Neurons in Culture
Homer1 (orange) and Bassoon (red) localize to the synapses of healthy neurons (blue), while Protein Kinase A (green) is found all over.
READ MORE >

Featured Center News

October 17, 2024

Thank you for attending the 2024 Conte Center Symposium!

The Conte Center thanks all the attendees, industry professionals, and invited speakers for participating in the 2024 Symposium. We look forward to seeing you at the next Symposium in Spring 2026.

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May 2025

Center work presented at the 2025 Modulation of Neural Circuits and Behavior Conference in Switzerland

Dr. Kevin Mastro gave an exciting update on our current work in brain development and psychiatric illness. Hope you had a chance to see his amazing talk.

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August 2024

An Interview with Olúmídé Fagboyegun

In an interview with Boston Children's Hospital, Olúmídé Fagboyegun sat down with Nancy Fliesler to discuss his interests in science and building community.

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